THE XANTHINE OXIDASE CONTENT OF RAT LIVER IN RIBOFLAVIN DEFICIENCY
نویسندگان
چکیده
منابع مشابه
Synthesis of xanthine oxidase by rat liver slices in vitro.
The influence of dietary protein on the activity of rat liver xanthine oxidase has been studied by several workers (l-5) and would point to a relationship between the availability of amino acids and the activity of liver xanthine oxidase (2). It has been demonstrated that the loss of liver xanthine oxidase activity in the rat greatly exceeds the loss of liver protein during acute inanition (l),...
متن کاملA colorimetric assay for xanthine oxidase in rat liver homogenates.
In studying the oxidation of xanthine manometrically by using liver homogenate systems (l), certain irregularities in the method have become evident to the authors. Occasionally an oxygen consumption has been observed after 2 to 3 hours of incubation which is greatly in excess of the theoretical requirement for the complete oxidation of the xanthine substrate. In certain experiments the measure...
متن کاملSensitivity of rat liver xanthine oxidase to amino acid analogues.
There is ample evidence in the literature concerning the labile nature of rat liver xanthine oxidase and its dependence on dietary protein. McQuarrie and Venosa (1) observed a large drop in the enzyme activity when the protein content of the ration was reduced from 25 to 10 per cent. Miller (2) noticed that a 7 day inanition caused a loss of xanthine oxidase activity in rat liver which exceeded...
متن کاملReaction of 5-ethynyluracil with rat liver xanthine oxidase.
5-Ethynyluracil is a time-dependent and tight binding inhibitor of xanthine oxidase. The maximal value of the first-order rate constant for onset of inhibition is 0.01 s-1, and the concentration of 5-ethynyluracil which gives one-half of this value is 190 microM. Because the t1/2 for formation of active enzyme from inhibited enzyme is greater than 30 h in the absence of NADH, inhibition of xant...
متن کاملthe washback effect of discretepoint vs. integrative tests on the retention of content in knowledge tests
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1941
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)72856-1